Australian team have cured a type of cancer in mice and hope to start human trials within a year.
Professor Nigel McMillan and his team at Griffith University, Queensland, Australia have made a promising breakthrough in the search for a cure of cervical and other HPV caused cancers.
Read the full story here from the Gold Coast Bulletin:
The Griffith University scientists found the experimental drug alisertib rid mice of cancers of the cervix, skin, head and neck caused by the human papillomavirus.
While a vaccine for cervical cancer is available, it’s still the third biggest killer of women and survival rates are very low.
The researchers hope the drug may one day become a viable alternative to chemotherapy and radiation treatment.
Professor Nigel McMillan, who has been working with the University of Queensland’s Professor Brian Gabrielli, said it was an exciting breakthrough in his long mission to find a cure for cervical cancer.
“For the first time in a long time the mice are completely cured of cancer we gave them,” he said.
“A lot of our cancer therapies these days are very non-specific like chemotherapy and radiation so we’re trying to get something better.”
Prof McMillan said alisertib was already available in the US where in trials it had proven effective against blood cancers and some solid tumours.
“The nice thing about that is this is a drug that’s already gone into humans,” he said.
“We think we’ve discovered the most appropriate or new use for this drug. It means we can progress to clinical trials.”
Source: Gold Coast Bulletin: http://www.goldcoastbulletin.com.au/news/hope-for-experimental-drug-after-gold-coast-researchers-cure-type-of-cancer-in-mice/story-fnj94j0t-1227187715317
Alisertib (MLN8237) is an orally available selective aurora A kinase inhibitor. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferationAurora A dysregulation has been associated with high occurrence of cancer. (Source: wiki)